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Genome-wide characterization of mitochondrial DNA methylation in human brain

BACKGROUND: There is growing interest in the role of DNA methylation in regulating the transcription of mitochondrial genes, particularly in brain disorders characterized by mitochondrial dysfunction. Here, we present a novel approach to interrogate the mitochondrial DNA methylome at single base res...

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Detalles Bibliográficos
Autores principales: Devall, Matthew, Soanes, Darren M., Smith, Adam R., Dempster, Emma L., Smith, Rebecca G., Burrage, Joe, Iatrou, Artemis, Hannon, Eilis, Troakes, Claire, Moore, Karen, O’Neill, Paul, Al-Sarraj, Safa, Schalkwyk, Leonard, Mill, Jonathan, Weedon, Michael, Lunnon, Katie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885148/
https://www.ncbi.nlm.nih.gov/pubmed/36726473
http://dx.doi.org/10.3389/fendo.2022.1059120