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Patient specific real-time PCR in precision medicine – Validation of IG/TR based MRD assessment in lymphoid leukemia

Detection of patient- and tumor-specific clonally rearranged immune receptor genes using real-time quantitative (RQ)-PCR is an accepted method in the field of precision medicine for hematologic malignancies. As individual primers are needed for each patient and leukemic clone, establishing performan...

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Detalles Bibliográficos
Autores principales: Schilhabel, Anke, Szczepanowski, Monika, van Gastel-Mol, Ellen J., Schillalies, Janina, Ray, Jill, Kim, Doris, Nováková, Michaela, Dombrink, Isabel, van der Velden, Vincent H. J., Boettcher, Sebastian, Brüggemann, Monika, Kneba, Michael, van Dongen, Jacques J. M., Langerak, Anton W., Ritgen, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885152/
https://www.ncbi.nlm.nih.gov/pubmed/36727082
http://dx.doi.org/10.3389/fonc.2022.1111209