Small GTPase Ran: Depicting the nucleotide-specific conformational landscape of the functionally important C-terminus

The small GTPase Ran is the main regulator of the nucleo-cytoplasmic import and export through the nuclear pore complex. It functions as a molecular switch cycling between the GDP-bound inactive and GTP-bound active state. It consists of a globular (G) domain and a C-terminal region, which is bound...

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Detalles Bibliográficos
Autores principales: Czigleczki, Janka, de Resende Lara, Pedro Tulio, Dudas, Balint, Jang, Hyunbum, Perahia, David, Nussinov, Ruth, Balog, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885160/
https://www.ncbi.nlm.nih.gov/pubmed/36726377
http://dx.doi.org/10.3389/fmolb.2023.1111574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885160/
https://www.ncbi.nlm.nih.gov/pubmed/36726377
http://dx.doi.org/10.3389/fmolb.2023.1111574

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