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Small GTPase Ran: Depicting the nucleotide-specific conformational landscape of the functionally important C-terminus
The small GTPase Ran is the main regulator of the nucleo-cytoplasmic import and export through the nuclear pore complex. It functions as a molecular switch cycling between the GDP-bound inactive and GTP-bound active state. It consists of a globular (G) domain and a C-terminal region, which is bound...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885160/ https://www.ncbi.nlm.nih.gov/pubmed/36726377 http://dx.doi.org/10.3389/fmolb.2023.1111574 |