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In vitro beta-cell killing models using immune cells and human pluripotent stem cell-derived islets: Challenges and opportunities
Type 1 diabetes (T1D) is a disease of both autoimmunity and β-cells. The β-cells play an active role in their own demise by mounting defense mechanisms that are insufficient at best, and that can become even deleterious in the long term. This complex crosstalk is important to understanding the physi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885197/ https://www.ncbi.nlm.nih.gov/pubmed/36726462 http://dx.doi.org/10.3389/fendo.2022.1076683 |