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Identification of MTHFD2 as a prognostic biomarker and ferroptosis regulator in triple-negative breast cancer
BACKGROUND: Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) is a mitochondrial bifunctional enzyme encoded in the nucleus. It plays a significant role in the regulation of glucose, nucleic acid, and folate metabolism, and maintains redox balance in the cells. The present study aimed at elucidatin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885267/ https://www.ncbi.nlm.nih.gov/pubmed/36726381 http://dx.doi.org/10.3389/fonc.2023.1098357 |