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Efficacy of sofpironium bromide gel on clozapine-induced hypersalivation in patients with treatment-resistant schizophrenia: double-blind, controlled crossover study

BACKGROUND: Hypersalivation is a major side-effect of clozapine in patients with treatment-resistant schizophrenia. AIMS: We investigated the efficacy of topical anticholinergic formulation sofpironium bromide gel for improving hypersalivation in patients with treatment-resistant schizophrenia recei...

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Detalles Bibliográficos
Autores principales: Amano, Yuhei, Mazda, Jun, Amano, Koichi, Ohi, Kazutaka, Shioiri, Toshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885354/
https://www.ncbi.nlm.nih.gov/pubmed/36636808
http://dx.doi.org/10.1192/bjo.2022.630