Identification of Natural Products Inhibiting SARS-CoV-2 by Targeting Viral Proteases: A Combined in Silico and in Vitro Approach

[Image: see text] In this study, an integrated in silico–in vitro approach was employed to discover natural products (NPs) active against SARS-CoV-2. The two SARS-CoV-2 viral proteases, i.e., main protease (M(pro)) and papain-like protease (PL(pro)), were selected as targets for the in silico study....

Descripción completa

Detalles Bibliográficos
Autores principales: Wasilewicz, Andreas, Kirchweger, Benjamin, Bojkova, Denisa, Abi Saad, Marie Jose, Langeder, Julia, Bütikofer, Matthias, Adelsberger, Sigrid, Grienke, Ulrike, Cinatl Jr., Jindrich, Petermann, Olivier, Scapozza, Leonardo, Orts, Julien, Kirchmair, Johannes, Rabenau, Holger F., Rollinger, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885530/
https://www.ncbi.nlm.nih.gov/pubmed/36651644
http://dx.doi.org/10.1021/acs.jnatprod.2c00843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885530/
https://www.ncbi.nlm.nih.gov/pubmed/36651644
http://dx.doi.org/10.1021/acs.jnatprod.2c00843

Ejemplares similares