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Comparison of the Antiviral Activity of Remdesivir, Chloroquine, and Interferon-β as Single or Dual Agents Against the Human Beta-Coronavirus OC43

The human beta-coronavirus strain, OC43, provides a useful model for testing the antiviral activity of various agents. We compared the activity of several antiviral drugs against OC43, including remdesivir, chloroquine, interferon (IFN)-β, IFN-λ1, and IFN-λ4, in two distinct cell types: human colore...

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Detalles Bibliográficos
Autores principales: Hickerson, Brady T., Sheikh, Faruk, Donnelly, Raymond P., Ilyushina, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885548/
https://www.ncbi.nlm.nih.gov/pubmed/36651846
http://dx.doi.org/10.1089/jir.2022.0210