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The presence of cerebellar B cell aggregates is associated with a specific chemokine profile in the cerebrospinal fluid in a mouse model of multiple sclerosis

BACKGROUND: The presence of meningeal ectopic lymphoid structures (ELS) in a subgroup of patients diagnosed with secondary progressive multiple sclerosis (SPMS) corresponds to a pronounced cortical inflammation and an aggravated disease course. In MP4-induced experimental autoimmune encephalomyeliti...

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Detalles Bibliográficos
Autores principales: Schropp, Verena, Chunder, Rittika, Dietel, Barbara, Tacke, Sabine, Kuerten, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885581/
https://www.ncbi.nlm.nih.gov/pubmed/36717913
http://dx.doi.org/10.1186/s12974-023-02695-z