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Decreased ratios of matrix metalloproteinases to tissue-type inhibitors in cerebrospinal fluid in sporadic and hereditary cerebral amyloid angiopathy

BACKGROUND: To evaluate the potential of cerebrospinal fluid (CSF) levels of matrix metalloproteinases and tissue-type inhibitors (MMP; TIMP), and ratios of MMPs to TIMPs, to function as biomarkers for sporadic or hereditary cerebral amyloid angiopathy (CAA). METHODS: CSF concentrations of the matri...

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Detalles Bibliográficos
Autores principales: Vervuurt, Marc, de Kort, Anna M., Jäkel, Lieke, Kersten, Iris, Abdo, Wilson F., Schreuder, Floris H. B. M., Rasing, Ingeborg, Terwindt, Gisela M., Wermer, Marieke J. H., Greenberg, Steven M., Klijn, Catharina J. M., Kuiperij, H. Bea, Verbeek, Marcel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885599/
https://www.ncbi.nlm.nih.gov/pubmed/36717932
http://dx.doi.org/10.1186/s13195-023-01171-3