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Integrated multi-dimensional analysis highlights DHCR7 mutations involving in cholesterol biosynthesis and contributing therapy of gastric cancer

BACKGROUND: Genetic background plays an important role in the occurrence and development of gastric cancer (GC). With the application of genome-wide association study (GWAS), an increasing number of tumor susceptibility genes in gastric cancer have been discovered. While little of them can be furthe...

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Detalles Bibliográficos
Autores principales: Chen, Yuqi, Yan, Wenying, Yang, Kexi, Qian, Yiting, Chen, Yanjun, Wang, Ruoqin, Zhu, Jinghan, He, Yuxin, Wu, Hongya, Zhang, Guangbo, Shi, Tongguo, Chen, Weichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885627/
https://www.ncbi.nlm.nih.gov/pubmed/36710342
http://dx.doi.org/10.1186/s13046-023-02611-6