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Loop pathways are responsible for tuning the accumulation of C19- and C22-sterol intermediates in the mycobacterial phytosterol degradation pathway

4-Androstene-3,17-dione (4-AD) and 22-hydroxy-23,24-bisnorchol-4-ene-3-one (BA) are the most important and representative C19- and C22-steroidal materials. The optimalization of sterol production with mycobacterial phytosterol conversion has been investigated for decades. One of the major challenges...

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Detalles Bibliográficos
Autores principales: Song, Shikui, He, Jianxin, Gao, Meng, Huang, Yongqi, Cheng, Xiyao, Su, Zhengding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885637/
https://www.ncbi.nlm.nih.gov/pubmed/36710325
http://dx.doi.org/10.1186/s12934-022-02008-8