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ADAM12 promotes clear cell renal cell carcinoma progression and triggers EMT via EGFR/ERK signaling pathway

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is a major worldwide health problem due to its high prevalence and mortality rate. A disintegrin and metalloproteinase 12 (ADAM12) is aberrantly expressed in various cancers and plays an important role in tumor progression. However, its explicit ef...

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Detalles Bibliográficos
Autores principales: Xu, Jinming, Wang, Yan, Jiang, Jiahao, Yin, Cong, Shi, Bentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885678/
https://www.ncbi.nlm.nih.gov/pubmed/36717944
http://dx.doi.org/10.1186/s12967-023-03913-1