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Effect of necrostatin-1 on sciatic nerve crush injury in rat models

BACKGROUND: Necrostatin-1 (Nec-1) is an inhibitor of the receptor interacting protein (RIP)1 kinase, which acts as an inhibitor of necroptosis, a special form of necrosis. In the present study, the effect of Nec-1 on peripheral nerve injury (PNI) was investigated. METHODS: The PNI model was establis...

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Detalles Bibliográficos
Autores principales: Yu, Chen, Wang, Xiaoxu, Qin, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885697/
https://www.ncbi.nlm.nih.gov/pubmed/36717933
http://dx.doi.org/10.1186/s13018-023-03565-3