Increased β1-adrenergic receptor antibody confers a vulnerable substrate for atrial fibrillation via mediating Ca(2+) mishandling and atrial fibrosis in active immunization rabbit models

Background: Autoimmune disorder is the emerging mechanism of atrial fibrillation (AF). The β1-adrenergic receptor antibody (β1-AAb) is associated with AF progress. Our study aims to investigate whether β1-AAbs involves in atrial vulnerable substrate by mediating Ca(2+) mishandling and atrial fibrosi...

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Detalles Bibliográficos
Autores principales: Sun, Huaxin, Song, Jie, Li, Kai, Li, Yao, Shang, Luxiang, Zhou, Qina, Lu, Yanmei, Zong, Yazhen, He, Xiuyuan, Kari, Muzappar, Yang, Hang, Zhou, Xianhui, Zhang, Ling, Tang, Baopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Cardiovascular System & Vascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885845/
https://www.ncbi.nlm.nih.gov/pubmed/36597894
http://dx.doi.org/10.1042/CS20220654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885845/
https://www.ncbi.nlm.nih.gov/pubmed/36597894
http://dx.doi.org/10.1042/CS20220654

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