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Microscopic polyangiitis plasma-derived exosomal miR-1287-5p induces endothelial inflammatory injury and neutrophil adhesion by targeting CBL

BACKGROUND: An inflammatory environment around the vessel wall caused by leukocyte infiltration is one of the characteristic histopathological features of microscopic polyangiitis (MPA); however, the pathogenic mechanisms are not fully understood. Studies have found that circulating microRNA (miRNA)...

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Detalles Bibliográficos
Autores principales: Zhu, Yan, Liu, Liu, Chu, Liepeng, Lan, Jingjing, Wei, Jingsi, Li, Wei, Xue, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885867/
https://www.ncbi.nlm.nih.gov/pubmed/36726727
http://dx.doi.org/10.7717/peerj.14579