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The Role of Immune Mechanisms, Inflammatory Pathways, and Macrophage Activation Syndrome in the Pathogenesis of Hemophagocytic Lymphohistiocytosis

This review article describes the pathophysiology of hemophagocytic lymphohistiocytosis (HLH). The condition is characterized by excessive stimulation of inflammatory cytokines, lymphocytes, and macrophages, leading to hyperinflammatory disorder with immune dysfunction. The main clinical and diagnos...

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Detalles Bibliográficos
Autores principales: Bseiso, Omair, Zahdeh, Anas, Isayed, Obay, Mahagna, Seewar, Bseiso, Anan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885896/
https://www.ncbi.nlm.nih.gov/pubmed/36726930
http://dx.doi.org/10.7759/cureus.33175