Peripheral blood cellular profile at pre-lymphodepletion is associated with CD19-targeted CAR-T cell-associated neurotoxicity

BACKGROUND: Infusion of second generation autologous CD19-targeted chimeric antigen receptor (CAR) T cells in patients with R/R relapsed/refractory B-cell lymphoma (BCL) is affected by inflammatory complications, such as Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS). Current literat...

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Detalles Bibliográficos
Autores principales: De Matteis, Serena, Dicataldo, Michele, Casadei, Beatrice, Storci, Gianluca, Laprovitera, Noemi, Arpinati, Mario, Maffini, Enrico, Cortelli, Pietro, Guarino, Maria, Vaglio, Francesca, Naddeo, Maria, Sinigaglia, Barbara, Zazzeroni, Luca, Guadagnuolo, Serafina, Tomassini, Enrica, Bertuccio, Salvatore Nicola, Messelodi, Daria, Ferracin, Manuela, Bonafè, Massimiliano, Zinzani, Pier Luigi, Bonifazi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886226/
https://www.ncbi.nlm.nih.gov/pubmed/36726971
http://dx.doi.org/10.3389/fimmu.2022.1058126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886226/
https://www.ncbi.nlm.nih.gov/pubmed/36726971
http://dx.doi.org/10.3389/fimmu.2022.1058126

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