Nanobodies combined with DNA-PAINT super-resolution reveal a staggered titin nanoarchitecture in flight muscles

Sarcomeres are the force-producing units of all striated muscles. Their nanoarchitecture critically depends on the large titin protein, which in vertebrates spans from the sarcomeric Z-disc to the M-band and hence links actin and myosin filaments stably together. This ensures sarcomeric integrity an...

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Detalles Bibliográficos
Autores principales: Schueder, Florian, Mangeol, Pierre, Chan, Eunice HoYee, Rees, Renate, Schünemann, Jürgen, Jungmann, Ralf, Görlich, Dirk, Schnorrer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886278/
https://www.ncbi.nlm.nih.gov/pubmed/36645127
http://dx.doi.org/10.7554/eLife.79344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886278/
https://www.ncbi.nlm.nih.gov/pubmed/36645127
http://dx.doi.org/10.7554/eLife.79344

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