A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite

The malaria parasite Plasmodium falciparum synthesizes significant amounts of phospholipids to meet the demands of replication within red blood cells. De novo phosphatidylcholine (PC) biosynthesis via the Kennedy pathway is essential, requiring choline that is primarily sourced from host serum lysop...

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Detalles Bibliográficos
Autores principales: Ramaprasad, Abhinay, Burda, Paul-Christian, Calvani, Enrica, Sait, Aaron J, Palma-Duran, Susana Alejandra, Withers-Martinez, Chrislaine, Hackett, Fiona, Macrae, James, Collinson, Lucy, Gilberger, Tim Wolf, Blackman, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886279/
https://www.ncbi.nlm.nih.gov/pubmed/36576255
http://dx.doi.org/10.7554/eLife.82207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886279/
https://www.ncbi.nlm.nih.gov/pubmed/36576255
http://dx.doi.org/10.7554/eLife.82207

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