Prophylaxis and treatment of SARS-CoV-2 infection by an ACE2 receptor decoy in a preclinical animal model

The emergence of SARS-CoV-2 variants with highly mutated spike proteins has presented an obstacle to the use of monoclonal antibodies for the prevention and treatment of SARS-CoV-2 infection. We show that a high-affinity receptor decoy protein in which a modified ACE2 ectodomain is fused to a single...

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Detalles Bibliográficos
Autores principales: Tada, Takuya, Dcosta, Belinda M., Zhou, Hao, Landau, Nathaniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886562/
https://www.ncbi.nlm.nih.gov/pubmed/36741912
http://dx.doi.org/10.1016/j.isci.2023.106092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886562/
https://www.ncbi.nlm.nih.gov/pubmed/36741912
http://dx.doi.org/10.1016/j.isci.2023.106092

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