Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice

Canagliflozin (Cana), a clinically important anti-diabetes drug, leads to a 14% increase in median lifespan and a 9% increase in the 90th percentile age when given to genetically heterogeneous male mice from 7 months of age, but does not increase lifespan in female mice. A histopathological study wa...

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Detalles Bibliográficos
Autores principales: Snyder, Jessica M., Casey, Kerriann M., Galecki, Andrzej, Harrison, David E., Jayarathne, Hashan, Kumar, Navasuja, Macchiarini, Francesca, Rosenthal, Nadia, Sadagurski, Marianna, Salmon, Adam B., Strong, Randy, Miller, Richard A., Ladiges, Warren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886729/
https://www.ncbi.nlm.nih.gov/pubmed/35974129
http://dx.doi.org/10.1007/s11357-022-00641-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886729/
https://www.ncbi.nlm.nih.gov/pubmed/35974129
http://dx.doi.org/10.1007/s11357-022-00641-0

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