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BACE1: A Key Regulator in Alzheimer’s Disease Progression and Current Development of its Inhibitors

Background: Alzheimer’s disease (AD) is a chronic neurodegenerative disease with no specific disease-modifying treatment. β-secretase (BACE1) is considered the potential and rationale target because it is involved in the rate-limiting step, which produces toxic Aβ(42) peptides that leads to deposits...

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Detalles Bibliográficos
Autores principales:	Patel, Smith, Bansoad, Ankush Vardhaman, Singh, Rakesh, Khatik, Gopal L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2022
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886827/ https://www.ncbi.nlm.nih.gov/pubmed/34852746 http://dx.doi.org/10.2174/1570159X19666211201094031

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