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Age-dependent thrombin generation predicts 30-day mortality and symptomatic thromboembolism after multiple trauma
Trauma-induced coagulopathy (TIC) is a risk factor for death and is associated with deviations in thrombin generation. TIC prevalence and thrombin levels increase with age. We assayed in vivo and ex vivo thrombin generation in injured patients (n = 418) to specifically investigate how age impacts th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886925/ https://www.ncbi.nlm.nih.gov/pubmed/36717730 http://dx.doi.org/10.1038/s41598-023-28474-7 |