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Age-dependent thrombin generation predicts 30-day mortality and symptomatic thromboembolism after multiple trauma

Trauma-induced coagulopathy (TIC) is a risk factor for death and is associated with deviations in thrombin generation. TIC prevalence and thrombin levels increase with age. We assayed in vivo and ex vivo thrombin generation in injured patients (n = 418) to specifically investigate how age impacts th...

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Detalles Bibliográficos
Autores principales: Lesbo, Maj, Hviid, Claus V. B., Brink, Ole, Juul, Svend, Borris, Lars C., Hvas, Anne-Mette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886925/
https://www.ncbi.nlm.nih.gov/pubmed/36717730
http://dx.doi.org/10.1038/s41598-023-28474-7