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Stress-related exposures amplify the effects of genetic susceptibility on depression and anxiety

It is unclear whether and to what extent stress-related exposures moderate the effects of polygenic risk scores (PRSs) on depression and anxiety. We aimed to examine such moderation effects for a variety of stress-related exposures on depression and anxiety. We included 41,810 participants with both...

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Detalles Bibliográficos
Autores principales: Wang, Rujia, Hartman, Catharina A., Snieder, Harold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886926/
https://www.ncbi.nlm.nih.gov/pubmed/36717542
http://dx.doi.org/10.1038/s41398-023-02327-3