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The E3 ubiquitin ligases regulate PD-1/PD-L1 protein levels in tumor microenvironment to improve immunotherapy

The tumor microenvironment (TME) is the tumor surrounding environment, which is critical for tumor development and progression. TME is also involved in clinical intervention and treatment outcomes. Modulation of TME is useful for improving therapy strategies. PD-L1 protein on tumor cells interacts w...

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Detalles Bibliográficos
Autores principales: Hou, Bo, Chen, Ting, Zhang, He, Li, Jiatong, Wang, Peter, Shang, Guanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887025/
https://www.ncbi.nlm.nih.gov/pubmed/36733484
http://dx.doi.org/10.3389/fimmu.2023.1123244