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The E3 ubiquitin ligases regulate PD-1/PD-L1 protein levels in tumor microenvironment to improve immunotherapy
The tumor microenvironment (TME) is the tumor surrounding environment, which is critical for tumor development and progression. TME is also involved in clinical intervention and treatment outcomes. Modulation of TME is useful for improving therapy strategies. PD-L1 protein on tumor cells interacts w...
Autores principales: | Hou, Bo, Chen, Ting, Zhang, He, Li, Jiatong, Wang, Peter, Shang, Guanning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887025/ https://www.ncbi.nlm.nih.gov/pubmed/36733484 http://dx.doi.org/10.3389/fimmu.2023.1123244 |
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