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Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury

Macrophage/microglia polarization acts as an important part in regulating inflammatory responses in spinal cord injury (SCI). However, the regulation of inflammation of Schwann cell-derived exosomes (SCDEs) for SCI repair is still unclear. Therefore, we intend to find out the effect of SCDEs on regu...

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Detalles Bibliográficos
Autores principales: Ren, Jie, Zhu, Bin, Gu, Guangjin, Zhang, Wencan, Li, Junjin, Wang, Hongda, Wang, Min, Song, Xiaomeng, Wei, Zhijian, Feng, Shiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887051/
https://www.ncbi.nlm.nih.gov/pubmed/36717543
http://dx.doi.org/10.1038/s41419-023-05607-4