Cargando…

Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury

Macrophage/microglia polarization acts as an important part in regulating inflammatory responses in spinal cord injury (SCI). However, the regulation of inflammation of Schwann cell-derived exosomes (SCDEs) for SCI repair is still unclear. Therefore, we intend to find out the effect of SCDEs on regu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Jie, Zhu, Bin, Gu, Guangjin, Zhang, Wencan, Li, Junjin, Wang, Hongda, Wang, Min, Song, Xiaomeng, Wei, Zhijian, Feng, Shiqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887051/ https://www.ncbi.nlm.nih.gov/pubmed/36717543 http://dx.doi.org/10.1038/s41419-023-05607-4

Ejemplares similares

Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization
por: Gu, Guangjin, et al.
Publicado: (2023)

Pre-Treatment of Recombinant Mouse MFG-E8 Downregulates LPS-Induced TNF-α Production in Macrophages via STAT3-Mediated SOCS3 Activation
por: Aziz, Monowar, et al.
Publicado: (2011)

Human umbilical cord mesenchymal stem cell-derived exosomes loaded into a composite conduit promote functional recovery after peripheral nerve injury in rats
por: Tang, Haoshuai, et al.
Publicado: (2023)

MFG-E8 Regulates Microglial Phagocytosis of Apoptotic Neurons
por: Fuller, Abby D., et al.
Publicado: (2008)

Propofol suppresses microglial phagocytosis through the downregulation of MFG-E8
por: Cai, Xiaoying, et al.
Publicado: (2021)

Essential Role of MFG-E8 for Phagocytic Properties of Microglial Cells
por: Liu, Yong, et al.
Publicado: (2013)

TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway
por: Li, Ran, et al.
Publicado: (2018)

Autophagy induced by Schwann cell-derived exosomes promotes recovery after spinal cord injury in rats
por: Pan, Dayu, et al.
Publicado: (2021)

Quantitative iTRAQ proteomics reveal the proteome profiles of bone marrow mesenchymal stem cells after cocultures with Schwann cells in vitro
por: Ding, Han, et al.
Publicado: (2022)

Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity
por: Wunderlich, Claudia M., et al.
Publicado: (2013)

Macrophage/microglial Ezh2 facilitates autoimmune inflammation through inhibition of Socs3
por: Zhang, Xingli, et al.
Publicado: (2018)

Hypoxic lung adenocarcinoma‐derived exosomal miR‐1290 induces M2 macrophage polarization by targeting SOCS3
por: Gu, Jiahui, et al.
Publicado: (2023)

miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis
por: Liu, Wei, et al.
Publicado: (2021)

Proteomics analysis of Schwann cell-derived exosomes: a novel therapeutic strategy for central nervous system injury
por: Wei, Zhijian, et al.
Publicado: (2019)

STAT3 and SOCS3 Expression Patterns During Murine Placenta Development
por: San Martin, S., et al.
Publicado: (2013)

STAT3/SOCS3 axis contributes to the outcome of salmonid whirling disease
por: Saleh, Mona, et al.
Publicado: (2020)

Increased expression of STAT3 and SOCS3 in placenta from hyperglycemic rats
por: Justina, Vanessa Dela, et al.
Publicado: (2019)

Curcumin Regulates Anti-Inflammatory Responses by JAK/STAT/SOCS Signaling Pathway in BV-2 Microglial Cells
por: Porro, Chiara, et al.
Publicado: (2019)

MFG on track with Georgia plant upgrades
Publicado: (2020)

Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury
por: Yuan, Feifei, et al.
Publicado: (2023)

Obesity Attenuates Ventilator-Induced Lung Injury by Modulating the STAT3–SOCS3 Pathway
por: Wu, Shih-Wei, et al.
Publicado: (2021)

Neurogenesis in Neurodegenerative Diseases: Role of MFG-E8
por: Cheyuo, Cletus, et al.
Publicado: (2019)

Inhibition of JAK2/STAT3/SOCS3 signaling attenuates atherosclerosis in rabbit
por: Yang, Xilan, et al.
Publicado: (2020)

The JAK1/STAT3/SOCS3 axis in bone development, physiology, and pathology
por: Sims, Natalie A.
Publicado: (2020)

SHP2, SOCS3 and PIAS3 Expression Patterns in Medulloblastomas: Relevance to STAT3 Activation and Resveratrol-Suppressed STAT3 Signaling
por: Li, Cong, et al.
Publicado: (2016)

IL-9 promotes the pathogenesis of ulcerative colitis through STAT3/SOCS3 signaling
por: Tian, Linglin, et al.
Publicado: (2018)

IL-10/STAT3/SOCS3 Axis Is Involved in the Anti-inflammatory Effect of Benznidazole
por: Cevey, Ágata C., et al.
Publicado: (2019)

Tofacitinib Promotes Functional Recovery after Spinal Cord Injury by Regulating Microglial Polarization via JAK/STAT Signaling Pathway
por: Ma, Hongdao, et al.
Publicado: (2023)

The mechanism of oxymatrine on atopic dermatitis in mice based on SOCS1/JAK-STAT3 pathway
por: Han, Xianwei, et al.
Publicado: (2023)

The Pros1/Tyro3 axis protects against periodontitis by modulating STAT/SOCS signalling
por: Jiang, Lei, et al.
Publicado: (2019)

Suppressed androgen receptor expression promotes M2 macrophage reprogramming through the STAT3/SOCS3 pathway
por: Ma, Wenhan, et al.
Publicado: (2019)

NDRG2-mediated Modulation of SOCS3 and STAT3 Activity Inhibits IL-10 Production
por: Lee, Eun Byul, et al.
Publicado: (2010)

CUEDC2 controls osteoblast differentiation and bone formation via SOCS3–STAT3 pathway
por: Kim, Jung-Woo, et al.
Publicado: (2020)

Inhibition of MAPK and STAT3-SOCS3 by Sakuranetin Attenuated Chronic Allergic Airway Inflammation in Mice
por: Santana, Fernanda P. R., et al.
Publicado: (2019)

Upregulation of Complement Factor H by SOCS-1/3–STAT4 in Lung Cancer
por: Yoon, Yeon-Hee, et al.
Publicado: (2019)

SOCS Proteins in Macrophage Polarization and Function
por: Wilson, Heather M.
Publicado: (2014)

Regulation of Macrophage, Dendritic Cell, and Microglial Phenotype and Function by the SOCS Proteins
por: McCormick, Sarah M., et al.
Publicado: (2015)

Schwann Cell-Derived Exosomes Induce the Differentiation of Human Adipose-Derived Stem Cells Into Schwann Cells
por: Zhou, Nan, et al.
Publicado: (2022)

Breast Cancer-Derived Exosomes Alter Macrophage Polarization via gp130/STAT3 Signaling
por: Ham, Sunyoung, et al.
Publicado: (2018)

Dissociating STAT4 and STAT5 Signaling Inhibitory Functions of SOCS3: Effects on CD8 T Cell Responses
por: Hwang, Ji Young, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_b0sm8ggt1di7f02iss0emltg8e