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Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury
Macrophage/microglia polarization acts as an important part in regulating inflammatory responses in spinal cord injury (SCI). However, the regulation of inflammation of Schwann cell-derived exosomes (SCDEs) for SCI repair is still unclear. Therefore, we intend to find out the effect of SCDEs on regu...
Autores principales: | Ren, Jie, Zhu, Bin, Gu, Guangjin, Zhang, Wencan, Li, Junjin, Wang, Hongda, Wang, Min, Song, Xiaomeng, Wei, Zhijian, Feng, Shiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887051/ https://www.ncbi.nlm.nih.gov/pubmed/36717543 http://dx.doi.org/10.1038/s41419-023-05607-4 |
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