Targeted inhibition of RBPJ transcription complex alleviates the exhaustion of CD8(+) T cells in hepatocellular carcinoma

Impaired function of CD8(+) T cells in hepatocellular carcinoma (HCC) is an important reason for acquired resistance. Compared with single-target inhibitors, small-molecule compounds that could both inhibit tumor cells and alleviate T cell exhaustion are more promising to reduce resistance. In this...

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Detalles Bibliográficos
Autores principales: Pan, Banglun, Wang, Zengbin, Zhang, Xiaoxia, Shen, Shuling, Ke, Xiaoling, Qiu, Jiacheng, Yao, Yuxin, Wu, Xiaoxuan, Wang, Xiaoqian, Tang, Nanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887061/
https://www.ncbi.nlm.nih.gov/pubmed/36717584
http://dx.doi.org/10.1038/s42003-023-04521-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887061/
https://www.ncbi.nlm.nih.gov/pubmed/36717584
http://dx.doi.org/10.1038/s42003-023-04521-x

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