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Microbially produced vitamin B12 contributes to the lipid-lowering effect of silymarin

Silymarin has been used for improving hepatic damage and lipid disorders, but its action mechanism remains to be clarified. Here, we investigate the contributions of the gut microbiota to the improvement of liver lipid metabolism by silymarin. We find i) strong and significant microbial shifts upon...

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Detalles Bibliográficos
Autores principales: Sun, Wen-Long, Hua, Sha, Li, Xin-Yu, Shen, Liang, Wu, Hao, Ji, Hong-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887073/
https://www.ncbi.nlm.nih.gov/pubmed/36717576
http://dx.doi.org/10.1038/s41467-023-36079-x