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Steps of actin filament branch formation by Arp2/3 complex investigated with coarse-grained molecular dynamics

The nucleation of actin filament branches by the Arp2/3 complex involves activation through nucleation promotion factors (NPFs), recruitment of actin monomers, and binding of the complex to the side of actin filaments. Because of the large system size and processes that involve flexible regions and...

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Detalles Bibliográficos
Autores principales: Zhang, Shuting, Vavylonis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887124/
https://www.ncbi.nlm.nih.gov/pubmed/36733458
http://dx.doi.org/10.3389/fcell.2023.1071977