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Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells

Bladder cancer is the most common malignancy of the urinary system. Efforts to identify innovative and effective therapies for bladder cancer are urgently needed. Recent studies have identified the BRD4 protein as the critical factor in regulation of cell proliferation and apoptosis in bladder cance...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Li, Baohu, Zhang, Wenkai, Li, Zhuoyue, Jiang, Bo, Hou, Sichuan, Ma, Shumin, Qin, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887192/
https://www.ncbi.nlm.nih.gov/pubmed/36733715
http://dx.doi.org/10.3389/fchem.2023.1121724