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Modified fibrin hydrogel for sustained delivery of RNAi lipopolyplexes in skeletal muscle
RNA interference is a promising therapeutical approach presently hindered by delivery concerns such as rapid RNA degradation and targeting of individual tissues. Injectable hydrogels are one potentially simple and direct route towards overcoming these barriers. Here we report on the utility of a com...
Autores principales: | Ngarande, Ellen, Doubell, Emma, Tamgue, Ousman, Mano, Manuel, Human, Paul, Giacca, Mauro, Davies, Neil Hamer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887344/ https://www.ncbi.nlm.nih.gov/pubmed/36726610 http://dx.doi.org/10.1093/rb/rbac101 |
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