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3D genome alterations in T cells associated with disease activity of systemic lupus erythematosus

OBJECTIVES: Three-dimensional (3D) genome alterations can dysregulate gene expression by rewiring physical interactions within chromosomes in a tissue-specific or cell-specific manner and lead to diseases. We aimed to elucidate the 3D genome structure and its role in gene expression networks dysregu...

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Detalles Bibliográficos
Autores principales: Zhao, Ming, Feng, Delong, Hu, Longyuan, Liu, Lin, Wu, Jiali, Hu, Zhi, Long, Haojun, Kuang, Qiqi, Ouyang, Lianlian, Lu, Qianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887402/
https://www.ncbi.nlm.nih.gov/pubmed/36690410
http://dx.doi.org/10.1136/ard-2022-222653