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cvlr: finding heterogeneously methylated genomic regions using ONT reads

SUMMARY: Nanopore reads encode information on the methylation status of cytosines in CpG dinucleotides. The length of the reads makes it comparatively easy to look at patterns consisting of multiple loci; here, we exploit this property to search for regions where one can define subpopulations of mol...

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Detalles Bibliográficos
Autores principales: Raineri, Emanuele, Alberola i Pla, Mariona, Dabad, Marc, Heath, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887406/
https://www.ncbi.nlm.nih.gov/pubmed/36726731
http://dx.doi.org/10.1093/bioadv/vbac101