Deep learning predicts the impact of regulatory variants on cell-type-specific enhancers in the brain

MOTIVATION: Previous studies have shown that the heritability of multiple brain-related traits and disorders is highly enriched in transcriptional enhancer regions. However, these regions often contain many individual variants, while only a subset of them are likely to causally contribute to a trait...

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Detalles Bibliográficos
Autores principales: Zheng, An, Shen, Zeyang, Glass, Christopher K, Gymrek, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887460/
https://www.ncbi.nlm.nih.gov/pubmed/36726730
http://dx.doi.org/10.1093/bioadv/vbad002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887460/
https://www.ncbi.nlm.nih.gov/pubmed/36726730
http://dx.doi.org/10.1093/bioadv/vbad002

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