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Deep learning predicts the impact of regulatory variants on cell-type-specific enhancers in the brain
MOTIVATION: Previous studies have shown that the heritability of multiple brain-related traits and disorders is highly enriched in transcriptional enhancer regions. However, these regions often contain many individual variants, while only a subset of them are likely to causally contribute to a trait...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887460/ https://www.ncbi.nlm.nih.gov/pubmed/36726730 http://dx.doi.org/10.1093/bioadv/vbad002 |