ADATscan – A flexible tool for scanning exomes for wobble inosine-dependent codons reveals a neurological bias for genes enriched in such codons in humans and mice

The conversion of adenosine to inosine at the wobble position of select tRNAs is essential for decoding specific codons in bacteria and eukarya. In eukarya, wobble inosine modification is catalyzed by the heterodimeric ADAT complex containing ADAT2 and ADAT3. Human individuals homozygous for loss of...

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Detalles Bibliográficos
Autores principales: Longan, Emery R., Ramos, Jillian, Fu, Dragony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887483/
https://www.ncbi.nlm.nih.gov/pubmed/36733466
http://dx.doi.org/10.17912/micropub.biology.000675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887483/
https://www.ncbi.nlm.nih.gov/pubmed/36733466
http://dx.doi.org/10.17912/micropub.biology.000675

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