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Oxysophoridine protects against cerebral ischemia/reperfusion injury via inhibition of TLR4/p38MAPK-mediated ferroptosis

Oxysophoridine (OSR) is an alkaloid extracted from Sophora alopecuroides L. and exerts beneficial effects in cerebral ischemia/reperfusion (I/R) injury. However, the molecular mechanism underlying the regulatory effects of OSR in cerebral I/R injury remains unclear. In the present study, a cerebral...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Ma, Mingming, Li, Lei, Fang, Gaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887505/
https://www.ncbi.nlm.nih.gov/pubmed/36601753
http://dx.doi.org/10.3892/mmr.2023.12931