Structural basis underlying the synergism of NADase and SLO during group A Streptococcus infection

Group A Streptococcus (GAS) is a strict human pathogen possessing a unique pathogenic trait that utilizes the cooperative activity of NAD(+)-glycohydrolase (NADase) and Streptolysin O (SLO) to enhance its virulence. How NADase interacts with SLO to synergistically promote GAS cytotoxicity and intrac...

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Detalles Bibliográficos
Autores principales: Tsai, Wei-Jiun, Lai, Yi-Hsin, Shi, Yong-An, Hammel, Michal, Duff, Anthony P., Whitten, Andrew E., Wilde, Karyn L., Wu, Chun-Ming, Knott, Robert, Jeng, U-Ser, Kang, Chia-Yu, Hsu, Chih-Yu, Wu, Jian-Li, Tsai, Pei-Jane, Chiang-Ni, Chuan, Wu, Jiunn-Jong, Lin, Yee-Shin, Liu, Ching-Chuan, Senda, Toshiya, Wang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887584/
https://www.ncbi.nlm.nih.gov/pubmed/36721030
http://dx.doi.org/10.1038/s42003-023-04502-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887584/
https://www.ncbi.nlm.nih.gov/pubmed/36721030
http://dx.doi.org/10.1038/s42003-023-04502-0

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