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Structural basis underlying the synergism of NADase and SLO during group A Streptococcus infection
Group A Streptococcus (GAS) is a strict human pathogen possessing a unique pathogenic trait that utilizes the cooperative activity of NAD(+)-glycohydrolase (NADase) and Streptolysin O (SLO) to enhance its virulence. How NADase interacts with SLO to synergistically promote GAS cytotoxicity and intrac...
Autores principales: | Tsai, Wei-Jiun, Lai, Yi-Hsin, Shi, Yong-An, Hammel, Michal, Duff, Anthony P., Whitten, Andrew E., Wilde, Karyn L., Wu, Chun-Ming, Knott, Robert, Jeng, U-Ser, Kang, Chia-Yu, Hsu, Chih-Yu, Wu, Jian-Li, Tsai, Pei-Jane, Chiang-Ni, Chuan, Wu, Jiunn-Jong, Lin, Yee-Shin, Liu, Ching-Chuan, Senda, Toshiya, Wang, Shuying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887584/ https://www.ncbi.nlm.nih.gov/pubmed/36721030 http://dx.doi.org/10.1038/s42003-023-04502-0 |
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