Synthesis and Comprehensive in Vivo Activity Profiling of Olean-12-en-28-ol, 3β-Pentacosanoate in Experimental Autoimmune Encephalomyelitis: A Natural Remyelinating and Anti-Inflammatory Agent

[Image: see text] Multiple sclerosis (MS) treatment has received much attention, yet there is still no certain cure. We herein investigate the therapeutic effect of olean-12-en-28-ol, 3β-pentacosanoate (OPCA) on a preclinical model of MS. First, OPCA was synthesized semisynthetically and characteriz...

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Detalles Bibliográficos
Autores principales: Senol, Halil, Ozgun-Acar, Ozden, Dağ, Aydan, Eken, Ahmet, Guner, Hüseyin, Aykut, Zaliha Gamze, Topcu, Gulacti, Sen, Alaattin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887603/
https://www.ncbi.nlm.nih.gov/pubmed/36598820
http://dx.doi.org/10.1021/acs.jnatprod.2c00798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887603/
https://www.ncbi.nlm.nih.gov/pubmed/36598820
http://dx.doi.org/10.1021/acs.jnatprod.2c00798

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