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Synthesis and Comprehensive in Vivo Activity Profiling of Olean-12-en-28-ol, 3β-Pentacosanoate in Experimental Autoimmune Encephalomyelitis: A Natural Remyelinating and Anti-Inflammatory Agent

[Image: see text] Multiple sclerosis (MS) treatment has received much attention, yet there is still no certain cure. We herein investigate the therapeutic effect of olean-12-en-28-ol, 3β-pentacosanoate (OPCA) on a preclinical model of MS. First, OPCA was synthesized semisynthetically and characteriz...

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Detalles Bibliográficos
Autores principales:	Senol, Halil, Ozgun-Acar, Ozden, Dağ, Aydan, Eken, Ahmet, Guner, Hüseyin, Aykut, Zaliha Gamze, Topcu, Gulacti, Sen, Alaattin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society and American Society of Pharmacognosy 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887603/ https://www.ncbi.nlm.nih.gov/pubmed/36598820 http://dx.doi.org/10.1021/acs.jnatprod.2c00798

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