Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations

Experimental evolution studies have shown that weak antibiotic selective pressures (i.e., when the antibiotic concentrations are far below the minimum inhibitory concentration, MIC) can select resistant mutants, raising several unanswered questions. First, what are the lowest antibiotic concentratio...

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Detalles Bibliográficos
Autores principales: Pereira, Catia, Warsi, Omar M, Andersson, Dan I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887637/
https://www.ncbi.nlm.nih.gov/pubmed/36627817
http://dx.doi.org/10.1093/molbev/msad010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887637/
https://www.ncbi.nlm.nih.gov/pubmed/36627817
http://dx.doi.org/10.1093/molbev/msad010

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