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Cardiomyocyte cohesion is increased after ADAM17 inhibition

A Disintegrin And Metalloprotease (ADAM) family proteins are involved in several cardiac diseases, and some ADAMs have been associated with cardiomyopathies. ADAM17 is known to cleave desmoglein 2 (DSG2), one of the proteins involved in the pathogenesis of arrhythmogenic cardiomyopathy (AC). Desmoso...

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Detalles Bibliográficos
Autores principales: Shoykhet, Maria, Waschke, Jens, Yeruva, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887658/
https://www.ncbi.nlm.nih.gov/pubmed/36733457
http://dx.doi.org/10.3389/fcell.2023.1021595