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Intramuscular administration of glyoxylate rescues swine from lethal cyanide poisoning and ameliorates the biochemical sequalae of cyanide intoxication

Cyanide—a fast-acting poison—is easy to obtain given its widespread use in manufacturing industries. It is a high-threat chemical agent that poses a risk of occupational exposure in addition to being a terrorist agent. FDA-approved cyanide antidotes must be given intravenously, which is not practica...

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Detalles Bibliográficos
Autores principales: Bebarta, Vik S, Shi, Xu, Zheng, Shunning, Hendry-Hofer, Tara B, Severance, Carter C, Behymer, Matthew M, Boss, Gerry R, Mahon, Sari, Brenner, Matthew, Knipp, Gregory T, Davisson, Vincent Jo, Peterson, Randall T, MacRae, Calum A, Rutter, Jared, Gerszten, Robert E, Nath, Anjali K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887668/
https://www.ncbi.nlm.nih.gov/pubmed/36326479
http://dx.doi.org/10.1093/toxsci/kfac116