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Pan-cancer patterns of cuproptosis markers reveal biologically and clinically relevant cancer subtypes

Cuproptosis is a newly discovered type of cell death triggered by copper accumulation. Here we exhibited the genetic profiles of 10 cuproptosis-associated genes (CuAGs) across 21 cancer types. Only 8.0% (627/7839) of tumors possessed at least 1 mutation on CuAGs, while the copy number amplifications...

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Detalles Bibliográficos
Autores principales: Bu, Fanqin, Li, Xiangji, Zhao, Yu, Bai, Liyi, Zhang, Shutian, Min, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887831/
https://www.ncbi.nlm.nih.gov/pubmed/36721175
http://dx.doi.org/10.1186/s40364-022-00446-5