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Development and validation of postoperative circulating tumor DNA combined with clinicopathological risk factors for recurrence prediction in patients with stage I-III colorectal cancer

BACKGROUND: Circulating tumor DNA (ctDNA) detection following curative-intent surgery could directly reflect the presence of minimal residual disease, the ultimate cause of clinical recurrence. However, ctDNA is not postoperatively detected in ≥ 50% of patients with stage I-III colorectal cancer (CR...

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Detalles Bibliográficos
Autores principales: Gao, Zhaoya, Huang, Dandan, Chen, Hui, Yang, Yong, An, Ke, Ding, Changmin, Yuan, Zheping, Zhai, Zhichao, Niu, Pengfei, Gao, Qingkun, Cai, Jinping, Zeng, Qingmin, Wang, Yanzhao, Hong, Yuming, Rong, Wanshui, Huang, Wensheng, Lei, Fuming, Wang, Xiaodong, Chen, Shiqing, Zhao, Xiaochen, Bai, Yuezong, Gu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887832/
https://www.ncbi.nlm.nih.gov/pubmed/36717891
http://dx.doi.org/10.1186/s12967-023-03884-3